Furthermore, MCL1 RNA expression positively associated with apoptosis and multiple inflammatory signaling pathways (such as IL6 JAK STAT3, and TNFA SIGNALING VIA NFKB) that converge on transcription factors reported to regulate MCL1 levels and are implicated in PCa progression (Figure 1D; Table S9).28 Here, IL6 is linked to posterior cortical atrophy.