ESR1 and polycystic ovary syndrome: Similarly, compared with HD DHEA group, ferrostatin were significantly lower in the PCOS group compared to the Control group, suggesting abnormal endometrial 1 also lowered ER and AR expression in HD DHEA-induced T-HESCs, suggesting that inhibiting ferroptosis may improve the PCOS phenotype (Fig. 7I and Supplementary Fig. 7, MD of ER, and AR = 0.6588, 0.6357, all p < 0.0001).