BRIC Type 1 and Type 2 are important differential diagnosis we should should consider with our participants with ABCB11 LoF (a1044x, c.2611-2 A > T, W239x) and ABCB11 SNV R1050H, especially since BRIC Type 2 has shown to have a correlation with gallstones. The gene discussed is ABCB11; the disease is benign recurrent intrahepatic cholestasis type 1.