For example, the SE-driven m6A readers IGF2BP2/3 stabilise DDX21 mRNA to facilitate the progression of acute myeloid leukaemia [49], and the SE-regulated lncRNA LINC01089 induces alternative splicing of DIAPH3 through m6A modification to drive hepatocellular carcinoma progression [50]. The gene discussed is DDX21; the disease is acute myeloid leukemia.