Though there have been few studies on the application of T to glioma, they have shown T mapping in patients to be effective in assessing the histologic grade [39], IDH gene mutation status [39, 40, 41] and 1p/19q codeletion status [40], as well as in differentiating between oedema related to intracranial metastases and gliomas [42]. This evidence concerns the gene IDH2 and central nervous system cancer.