These findings are consistent with other in vivo studies showing that genistein suppresses NF-κB signaling and pro-inflammatory cytokine release in models of systemic or organ-specific inflammation, such as high-fat diet-induced liver inflammation [42] and LPS-induced acute lung injury [43], further supporting its potential to mitigate neuroinflammation through similar mechanisms. The gene discussed is NFKB1; the disease is Hepatitis.