The significantly enriched pathways were Human papillomavirus infection, PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Protein digestion and absorption, Amoebiasis, AGE-RAGE signaling pathway in diabetic complications, Proteoglycans in cancer, Relaxin signaling pathway, NOD-like receptor signaling pathway, Small cell lung cancer, Malaria, and Bladder cancer (Fig. 2D). Here, RENBP is linked to amebiasis.