A literature search of these 20 genes found 9 that promote or suppress hepatocellular carcinoma (HCC): Dnajb2, Hdgfl2 (synonym Hrp2), Lncppara, Nlrp6, Wasf3 (Wave3), Zic1, Calb2, Itgb4, Mbd2; three with an active role in other cancers: Fam84b (Lratd2), Qprt, 1010001N08Rik (LncGata6); five with a role in other liver disease, cell protection or cell proliferation: Clvs2, Tnip1, Nfic, Rbpms2, Iffo2; and three with no information specific to liver function: Map10, Actl7b and Gm43401 (Table 2). This evidence concerns the gene ZIC1 and cancer.