Additionally, they noticed that the overexpression of GUSBP11 repressed the epithelial-to-mesenchymal transition in the triple-negative breast cancer cell lines by increasing E-cadherin and decreasing the expression of matrix metallopeptidase 2 (MMP2), MMP7, N-cadherin, and vimentin proteins.164. Here, MMP2 is linked to triple-negative breast carcinoma.