let-7a expression is decreased in several human cancers, such as prostate, breast, and gastric cancer, suggesting that this miRNA functions as a tumor suppressor166, 167, 168; this miRNA was down-regulated in liver cancer tissues and cell lines, whereas lncRNA RSU1P2 and testis-expressed protein 10 (Tex 10) were increased.169. The gene discussed is RSU1P2; the disease is liver cancer.