In this model, GM-CSF drives the proliferation of neutrophils, eosinophils, and monocytes [7,15]; IL-5 selectively promotes eosinophil expansion and recruitment to the pleural space [9,16]; and IL-6 amplifies the systemic inflammatory response and may foster epithelial-mesenchymal transition [17,18], a finding consistent with the vimentin positivity observed in the tumor cells. Here, CSF2 is linked to neoplasm.