Univariate regression showed that infarction location, atrial fibrillation, alkaline phosphatase (ALP), anion Gap (AG), aspartate aminotransferase (AST), serum creatinine (SCr), blood glucose, lactic acid, lactic dehydrogenase (LDH), pH, pO2, red blood cell distribution width (RDW), sodium ion, and blood urea nitrogen (BUN) were significantly associated with the occurrence of respiratory failure in IS patients. Here, RENBP is linked to infarction.