Meanwhile, the findings revealed that C-X-C motif chemokine 11 (CXCL11) levels (OR = 1.265, 95% CI = 0.985–1.625) and T-cell surface glycoprotein CD6 isoform levels (OR = 1.372, 95% CI = 1.069–1.761) increased risk of rosacea, while monocyte chemoattractant protein-1 levels (OR = 0.772, 95% CI = 0.621–0.960) and programmed cell death 1 ligand 1 levels (OR = 0.739, 95% CI = 0.557–0.981) decreased risk of rosacea. The gene discussed is CXCL11; the disease is rosacea.