CXCL8 and rosacea: A clinical study showed that serum chemokine levels in patients with rosacea are significantly higher than those in healthy control groups.[18] The expression of C-X-C motif chemokine ligand 8 (CXCL8) is elevated in patients with rosacea.[19] A cathelicidin LL37, antimicrobial peptide induces keratinocytes to release CXCL8, a key chemokine in rosacea.[20] Immune cells and inflammatory cytokines collectively contribute to the pathogenesis of rosacea.