Additionally, patients with carbohydrate antigen 19-9-positive CRC had a lower MICA-129 Met/Val variation, whereas those with carcinoembryonic antigen-positive CRC had a higher MICA-129 Met/Met variant (P = .0330/OR = 0.22 and P = .0034/OR = 2.99, respectively). The gene discussed is CEACAM5; the disease is colorectal carcinoma.