IL4 and neoplasm: Moreover, eosinophilic infiltration was inversely associated with LNM.[39] Elevated concentrations of follicular helper T cells are correlated with a decreased number of lymphatic metastases, and lower levels of TFH are associated with superior overall survival in patients with gastric cancer, which might exert a crucial role in suppressing the immune response to gastric cancer.[40] TH2 cells and innate lymphoid cells 2 are capable of stimulating tumor growth through the secretion of pro-tumor cytokines like IL-4, IL-5 and IL-13.