For example, downregulation of lncRNA-small nucleolar RNA host gene 7 was shown to inhibit inflammation and oxidative stress through the miR-425-5p/TRAF5/NF-κB axis.[17] These findings suggest that classical inflammatory pathways remain a key research focus in understanding the mechanistic role of ncRNAs in PD. This evidence concerns the gene NFKB1 and Parkinson disease.