found a high abundance of LncRNA-SOX2OT in NSCLC-derived exosomes, and LncRNA-SOX2OT promoted osteoclast differentiation by targeting the miRNA-1945p/RAC1 signaling axis and the TGF-β/pTHrP/RANKL signaling pathway [83]. The gene discussed is TNFSF11; the disease is non-small cell lung carcinoma.