CLC and asthma: As many of the identified key drivers in participants with asthma (Fig. 3) were eosinophil marker transcripts (e.g. CLC) and transcripts associated with eosinophil activity (e.g. CPA3), we next tested for correlation between key driver transcript expression and eosinophil and neutrophil abundances in bronchoalveolar lavage (BAL) fluid from participants with asthma.