TP53 and hepatocellular carcinoma: Although tumor vessel enlargement on CT arterial phase and reduced relative enhancement ratio on gadoxetic acid-enhanced MRI hepatobiliary phase have been significantly associated with P53-mutated HCC [13], the diagnostic specificity remains suboptimal at 63.4%, limiting its clinical utility.Weng et al. revealed significant heterogeneity in imaging manifestations of P53-mutated HCCs across different tumor diameters [14].