mregDC is the cell state with the highest expression of CXCL16 (the ligand for CXCR6), CXCR6 is the most highly expressed chemokine receptor on tumor-infiltrating CTLs, and mregDCs can also express and transpresent the survival factor IL-15, which supports CTL survival [61]. This evidence concerns the gene CXCR6 and neoplasm.