AQP3 and type 2 diabetes mellitus: A comparison of AQP3 mRNA levels from normoglycemic and type 2 diabetic donor islets in a larger cohort (n = 188) showed that AQP3 expression was elevated in type 2 diabetic islets (Fig. 4b, p value = 0.16; the lack of significance is likely due to the small sample size of T2D donors).