Additionally, DGEA showed an over-representation of multiple well-known marker genes for tumor-associated macrophages (TAMs) characterized by an immunosuppressive phenotype (also referred as to “M2-like” [48]) in GC BLOWvs GC BHIGH tumors, including the upregulation of CD14 (encoding one of the main differentiation markers of myeloid lineage), CD163, CD209, MRC1 (also known as CD206) and IL4R (Fig. 5A). The gene discussed is CD163; the disease is neoplasm.