TUBB4Aencompasses a broad spectrum, ranging from DYT4 to hypomyelination with atrophy of the basal ganglia and cerebellum (H-ABC) leukoencephalopathy, characterized by symptoms including dystonia, psychomotor delay, spasticity, ataxia, dysarthria, short stature, and microcephaly. DYT4 should not be categorized as an isolated dystonia. This evidence concerns the gene TUBB4A and Ataxia.