Although its role in Tfh biology has been underappreciated to date, GNG4 expression has appeared in DEG analyses of human T cells, including Tfh, thymic CD8αα T cells, cancer-associated subsets, and was listed after mass spectrometry studies of CD4 T cells stimulated in vitro (14, 25, 43, 67, 92, 99–107). This evidence concerns the gene CD4 and cancer.