However, SWI/SNF (BRG1) was recruited 6 hrs (similar time point of appearance of mRNA of IFN-β gene) after virus infection while Pol II was recruited 2–3 hrs earlier (Agalioti, Lomvardas et al. 2000, Lomvardas and Thanos 2002), which is consistent with the result from the same group showed that Pol II was recruited to transcribe even without the enhanceosome in vitro (Lomvardas and Thanos 2001). The gene discussed is IFNB1; the disease is viral infectious disease.