Our results suggest that RAB7B possessesstrong predictive capabilities for the development of liver cirrhosis.Moreover, RAB7B expression was consistently elevated in both internaland external data sets, with a significant positive correlation toCOL1α1 expression in cirrhotic patients compared with controls.Notably, RAB7B expression was particularly high in HSCs. The gene discussed is RAB7B; the disease is cirrhosis of liver.