TNF and Hepatic fibrosis: Interestingly,previous research has shown that cinnamtannin B1,the main bioactive compound found in Cinnamomum validinerve, can reduce immune cell infiltration and lower pro-inflammatorycytokine levels, including TNF-α and IL-6, when administeredintraperitoneally in infection models. Similarly, in rat models of hepatic fibrosis induced by carbon tetrachloride,compounds like epicatechin gallate and epigallocatechin gallate, derivedfrom Camellia sinensis, effectively suppressed keyinflammatory markers such as IL-17, transforming growth factor-beta(TGF-β), and TNF-α.