Our findings showed that for every 1‐year increase in age at menarche, the risk of endometrial cancer decreases by approximately 32%; for every 1 SD (about 30.3 nmol/L) increase in SHBG levels, the risk of endometrial cancer decreases by approximately 41%; and for every 1‐year increase in age at menopause, the risk of endometrial cancer decreases by approximately 24%. Here, SHBG is linked to endometrial cancer.