For instance, splicing factor 3b subunit 2 (SF3B2) and splicing factor 3b subunit 4 (SF3B4) are associated with craniofacial microsomia (MIM:164210; SyCL/P), and Nager syndrome (MIM:154400; SyOFC), respectively [11]. The gene discussed is SF3B2; the disease is craniofacial microsomia.