To test whether the mean of expression of XCL1 and CD8A can be an independent predictor for HCC prognosis, we conducted multivariable analysis to show that the low expression of XCL1 and CD8A is the independent prognostic factor for worse outcomes of HCC (p = .016, HR = 1.61) (Figure 5e). The gene discussed is CD8A; the disease is hepatocellular carcinoma.