XCR1 and hepatocellular carcinoma: Further experiments proved that overexpression of XCL1 inhibits HCC cell migration and invasion by affecting the epithelial–mesenchymal transition (EMT) and MAPK/PI3K/AKT signaling pathways.16 XCR1 is even suggested to be a prognostic marker that pinpoints targeted and immune-based therapy in hepatocellular carcinoma.13