This review found that drug-induced hyperprolactinemia commonly presents with menstrual disturbances, breast and lactation disorders, sexual dysfunction, and, less frequently, infertility and other reproductive symptoms. These effects were most often observed in women treated with antipsychotics, antidepressants, and other prolactin-elevating medications. The findings underscore the broad impact of elevated prolactin on reproductive and endocrine health. The gene discussed is PRL; the disease is sexual dysfunction.