MPO and eosinophilic granulomatosis with polyangiitis: For example, MPA is typically myeloperoxidase (MPO)-ANCA positive and lacks granulomatous inflammation, while eosinophilic GPA (EGPA) shows ANCA positivity in only around 30%-40% of cases (when positive, mostly MPO) and is associated with asthma and eosinophilia [5,6].