The search strategy combined Medical Subject Headings (MeSH) and free-text terms related to bariatric embolization, including “bariatric arterial embolization,” “left gastric artery embolization,” “ghrelin suppression,” “weight loss intervention,” “endovascular obesity therapy,” “gastric fundal embolization,” “non-surgical obesity management,” “ghrelin modulation,” “angiographic techniques,” and “metabolic outcomes.” Boolean operators (AND, OR, NOT) were applied to refine precision and ensure comprehensive retrieval of relevant sources. The gene discussed is GHRL; the disease is obesity due to melanocortin 4 receptor deficiency.