PRKN and Parkinson disease: Figure 5D displayed 16 key clusters in timeline view (#0 Parkinson’s disease, #1 mitochondrial fission, #2 parkin mediated mitophagy, #3 amyotrophic lateral sclerosis, #4 neuronal cell death, #5 mitochondrial dysfunction, #6 environmental neurotoxic chemicals-induced UPS dysfunction, #7 oxidative stress, #8 fluorogenic substrate, #9 stress-responsive transcription factor, #10 endo-lysosomal system interaction, #11 mitochondrial membrane potential, #12 mitochondrial damage, #13 independent mitochondrial protein quality control, #14 Huntington’s disease, #15 ischemia-reperfusion injury).