DAG1 and focal segmental glomerulosclerosis: Mutations in 5 of these proteins are known to cause FSGS lesions.18, 19, 20, 21, 22 Although no gFSGS has been found associated with mutations in DAG1 α and β dystroglycan, these molecules are important in the attachment of podocytes to basement membranes; and glomerular expression of dystroglycans has been proposed as able to differentiate MCD from pFSGS.23