ADGRE1 and infection: After CA04 infection, pulmonary expression of the four key genes in the B240+CA04 group was higher than that in the contemporaneous Saline+CA04 group: Gclc and Nqo1 differed significantly at 1–3 days (mixed−effects model Treatment × Virus × Time interaction; Tukey post−hoc test, both p < 0.05), and Adgre1 and Rsad2 differed significantly at 1–6 days (mixed−effects model Treatment × Virus × Time interaction; Tukey post−hoc test, both p < 0.01) (Figure 3B).