In addition, HuCCT1 cells, an intrahepatic CCA (ICC) cell line, expressed MRP1, MRP2, MRP4, MRP5, and MRP6, whereas KMBC cells, an extrahepatic CCA (ECC) cell line, expressed MRP1, MRP3, MRP4, and MRP5. This evidence concerns the gene ABCC5 and intrahepatic cholangiocarcinoma.