EGFR and squamous cell carcinoma: Nasopharyngeal carcinoma organoid studies demonstrate subtype-specific differences in chemoradiation sensitivity: the epidermoid carcinoma (EC) subtype exhibits a synergistic response to EGFR inhibitors in combination with radiotherapy, while squamous cell carcinoma (SC) and mixed squamous cell and epidermoid carcinoma (MSEC) subtypes show greater sensitivity to microtubule inhibitors—findings that inform precision combination therapy [62].