After the abortion and uterine curettage, the patient developed the classic triad of thrombotic microangiopathy in addition to high fever, hypovolemic shock, severe metabolic acidosis, acute kidney injury with anuria requiring hemodialysis, significant coagulopathy, and marked elevation of transaminases. The diagnostic workup was hampered by the unavailability of key tests, such as A Disintegrin And Metalloprotease with ThromboSpondin type 1 motif, member 13 (ADAMTS13) activity and complement genetic testing. The gene discussed is ADAMTS13; the disease is Genetic thrombotic microangiopathy.