From a preventive standpoint, this case underscores the importance of early recognition of the TMA triad in pregnancy and the postpartum period, systematic evaluation for TTP, STEC-HUS, and HELLP syndrome, and early referral to tertiary centers where complement testing and C5 inhibitors may be available, as these measures may reduce the risk of irreversible kidney damage. Here, C5 is linked to thrombotic thrombocytopenic purpura.