C3 and Disseminated intravascular coagulation: Nevertheless, the combination of (1) TMA triad, (2) reduced complement level (C3), (3) low risk of TTP according to the PLASMIC score and absence of need for plasmapheresis, (4) lack of preceding diarrhea suggestive of typical HUS, (5) negative cultures and no specific response to antimicrobial therapy, and (6) a clinical course incompatible with Hemolysis, Elevated Liver enzymes, and Low Platelets (HELLP) syndrome supported the diagnosis of complement-mediated TMA, likely triggered by obstetric complications and associated with disseminated intravascular coagulation (DIC).