As shown in Figure 4, compared with those in the control group, the expression levels of key node proteins of Fcγ R-mediated phagocytosis, including SYK, PI3K, PLCγ2, p-MARCKS, CDC42, and RAC, in the spleen samples of the malaria group decreased significantly (P< 0.01 or< 0.05). This evidence concerns the gene FCGR2A and malaria.