FLT3LG and myeloid sarcoma: Compared with HCs, NLGH patients showed decreased values of TNF-α, a potent inflammatory mediator, which contributes to immune cell infiltration into the CNS (26); of serum TNFSF12, involved in tissue remodeling and B cell activity, which is elevated in CSF of MS patients and associated with disease activity (31); and of FLT3LG, a key factor for the development and survival of dendritic cells which supports the adaptive immune responses (32).