We observed a significant increase in the frequency of CD8+NKG2A+ NK cells in T1D group compared to HD (p < 0.0028) and to T2D group (p = 0.0004) (Figure 2E, Table 3), alongside an increase in CD8+NKG2A− NK cells, and an almost twofold reduction in the proportion of double-negative CD8−NKG2A− NK cells (Figures 2F, G, Table 3). Here, CD8A is linked to type 2 diabetes mellitus.