It was proved that miRNAs, such as miR-17-92 cluster (miRs-17, -18a, -19a, -20a, -19b, and -92a) promotes tumor growth by targeting tumor suppressor genes such as phosphatase and tensin homolog deleted on chromosome 10 (PTEN) leading to a negative correlation with tumor-suppressive miRNAs as shown with miR-15a and miR-16-1 in chronic lymphocytic lymphoma[8,16]. The gene discussed is PTEN; the disease is neoplasm.