TFDP1 and cancer: The miR-1-3p has been widely reported to act as a tumor suppressor by downregulating multiple oncogenes across different cancer types (Dai et al., 2023; Zhang et al., 2019), whereas TFDP1 functions as a transcriptional co-factor that promotes oncogene expression and tumor progression in several malignancies (Sung et al., 2025; Ju et al., 2025).