SLC32A1 and Huntington disease: On the contrary, quantitative immunofluorescence analyses using anti-VGAT (vesicular GABA transporter; to label inhibitory presynapses) showed that zQ175+/- mice had a significantly lower VGAT puncta density than WT mice (Figs. 6B-6D), which was in line with a previous report that GABAergic synaptic transmission was impaired in HD mouse models 52.