Histological analysis further demonstrated that Syt7 knockdown mitigated CORT-induced myocardial injury including increased heart volume (Figure S4A-D), increased cardiomyocyte size (Figure S4E), cytoplasmic vacuolization (Figure S4F), and cardiac interstitial fibrosis (Figure S4G-H). Here, SYT7 is linked to Interstitial cardiac fibrosis.