P4HA2 and neoplasm: Regarding diagnostic performance, P4HA2 demonstrated AUC values above 0.9 in distinguishing tumor tissues from normal tissues in COAD, HNSC, ESCA, LIHC, LUSC, PCPG, READ, and STAD (Figure 14C), with an AUC of 0.815 in BRCA (Figure 14D).