-Significantly reduced scar thickness, vascularity, and pliability-Decreased collagen volume fraction and scar elevation index-Suppressed CD31 expression, indicating reduced angiogenesis-Lowered levels of p-AKT, p70S6K, and p-p70S6K-No adverse effects such as allergy, erythema, erosion, or dyspigmentation were observed. The gene discussed is AKT1; the disease is allergic disease.