NAT1 and neuroblastoma: To assess CT-induced inflammation responses in neuroblastoma cells, we analyzed the expression of pro-inflammatory cytokines IL-6, IL-8, and TNF-α and other inflammatory proteins such as SOD1, CAT, HMOX1, and NAT1(3). Our RT-qPCR data indicates that exposure to MC-LR significantly increased IL-6 expression (4.2-fold) while decreased the expression of SOD1 and CAT compared to vehicle-treated cells (Figure 2A).