Compared with the control group, the levels of FEV1/FVC, FEV1%pred, and PEF in the asthma group were significantly lower (all P-values < 0.001), while the levels of plasma eosinophil, IgE, leukotriene, and histamine were significantly higher (all P-values < 0.001). Here, IGHE is linked to asthma.