In the merged dataset, the expression levels of these six genes—DDR2, ENO3, ESM1, NMBR, PRKAB1, and PRPF19—showed significant differences between normal and endometriosis samples (DDR2, p < 0.001; ENO3, p < 0.001; ESM1, p < 0.001; NMBR, p = 0.002; PRKAB1, p < 0.001; PRPF19, p < 0.001). This evidence concerns the gene ESM1 and endometriosis.