In the GSE141549 validation cohort, only DDR2, ESM1, and PRKAB1 maintained the same expression trends as observed in the merged dataset, with statistically significant differences between normal and endometriosis samples (DDR2, p < 0.001; ESM1, p = 0.002; PRKAB1, p < 0.001). This evidence concerns the gene PRKAB1 and endometriosis.